CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Imbalance of rare CCR10+ CD8+ and CD4+ memory T cells in children at onset of type 1 diabetes
DOI 10.1055/s-0034-1375048
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Autor:innenB Upadhyaya, D Kuehn, S Ruhwald, M Bonsack, M Krassner, K Warnke, A Gavrisan, AG Ziegler, E Bonifacio
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Type 1 diabetes is a chronic autoimmune disease characterised by the presence of memory autoreactive CD4+ and CD8+ T cells that mediate islet beta cell destruction. We asked whether there are changes in the distributions of major and rare memory T cell subsets in the children with type 1 diabetes. Peripheral blood samples from 47 children at diabetes onset, aged 7 – 11 years, and from 47 age-matched autoantibody neg…
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Zitierempfehlung
B Upadhyaya, D Kuehn, S Ruhwald, M Bonsack, M Krassner, K Warnke, A Gavrisan, AG Ziegler, E Bonifacio (2014) Imbalance of rare CCR10+ CD8+ and CD4+ memory T cells in children at onset of type 1 diabetes. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1375048
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