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Effects of the DPP-4 inhibitor saxagliptin on early vascular changes in the retinal and systemic circulation

RE Schmieder, U Raff, S Schmidt, I Kistner, S Friedrich, P Bramlage, J Harazny, C Ott · Diabetologie und Stoffwechsel · Ausgabe 05/2014

DOI 10.1055/s-0034-1375092

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Autor:innenRE Schmieder, U Raff, S Schmidt, I Kistner, S Friedrich, P Bramlage, J Harazny, C Ott
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Background: Patients with diabetes mellitus are at increased risk for microvascular complications. Early changes in microcirculation are characterized by hyperperfusion (e.g. in the retina and kidney) and increased pulse wave reflection leading to increased aortic pressure. We investigated the effects of the DPP-4-inhibitor saxagliptin on early retinal microvascular changes. Methods: In this double-blind, controlled…

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RE Schmieder, U Raff, S Schmidt, I Kistner, S Friedrich, P Bramlage, J Harazny, C Ott (2014) Effects of the DPP-4 inhibitor saxagliptin on early vascular changes in the retinal and systemic circulation. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1375092

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