CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Hif2α in myeloid cells regulates angiogenesis in proliferative retinopathy
DOI 10.1055/s-0034-1375095
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Nachweis in CareLit
Autor:innenA Klotzsche-von Ameln, I Korovina, A Neuwirth, B Gercken, I Alexaki, T Chavakis
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Retinal hypoxia is the main trigger for pathological neovascularization (NV) in proliferative retinopathies (PR), such as diabetic retinopathy (DR). Synergisms between hypoxia, angiogenesis and innate immune response exist, which could be integrated at the level of the hypoxia-inducible factors (HIF). HIF2α is expressed in endothelial and myeloid cells. To study the role of myeloid cell HIF2α for pathologic NV in th…
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Zitierempfehlung
A Klotzsche-von Ameln, I Korovina, A Neuwirth, B Gercken, I Alexaki, T Chavakis (2014) Hif2α in myeloid cells regulates angiogenesis in proliferative retinopathy. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1375095
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