CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
The GLP-1 metabolite (9 – 37) improves myocardial function in the TAC model by reducing myocardial hypertrophy and improving glucose uptake
DOI 10.1055/s-0034-1375098
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Autor:innenJ Möllmann, R Stöhr, W Coumans, O Winz, AT Vogg, HJ Kaiser, C Lebherz, FM Mottaghy, JJ Luiken, JF Glatz, N Marx, M Lehrke
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Purpose: Diastolic dysfunction and myocardial hypertrophy are signs of hypertensive cardiomyopathy. GLP-1(7 – 37) is an incretin hormone which is released in response to nutritional stimuli from the gut and improves glucose metabolism by increasing glucose dependent insulin secretion from the pancreas. GLP-1(7 – 37) is rapidly cleaved to its inactive metabolite GLP-1(9 – 37) which can't bind to the GLP-1 receptor an…
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Zitierempfehlung
J Möllmann, R Stöhr, W Coumans, O Winz, AT Vogg, HJ Kaiser, C Lebherz, FM Mottaghy, JJ Luiken, JF Glatz, N Marx, M Lehrke (2014) The GLP-1 metabolite (9 – 37) improves myocardial function in the TAC model by reducing myocardial hypertrophy and improving glucose uptake. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1375098
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