CareLit · DOI-Nachweis · Diabetologie und Stoffwechsel
Metabolic footprint of the GLP-1 receptor agonist liraglutide in adolescent transgenic pigs with impaired incretin function
DOI 10.1055/s-0034-1375129
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Nachweis in CareLit
Autor:innenS Renner, E Streckel, C Braun-Reichhart, W Römisch-Margl, C Prehn, J Adamski, E Wolf
ZeitschriftDiabetologie und Stoffwechsel
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Aim: Metabolites can be very sensitive markers for the evaluation of drug efficiency and safety. We analyzed changes in the metabolome of adolescent pre-diabetic pigs expressing a dominant negative glucose-dependent insulinotropic polypeptide receptor (GIPRdn) after treatment with the GLP-1 receptor agonist liraglutide using a targeted metabolomics approach. Methods: 2-month-old GIPRdn transgenic pigs were treated w…
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Zitierempfehlung
S Renner, E Streckel, C Braun-Reichhart, W Römisch-Margl, C Prehn, J Adamski, E Wolf (2014) Metabolic footprint of the GLP-1 receptor agonist liraglutide in adolescent transgenic pigs with impaired incretin function. Diabetologie und Stoffwechsel (05). https://doi.org/10.1055/s-0034-1375129
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