CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Visceral hyposensitivity induced by congenitally elevated gut permeability turns to hypersensitivity after stress in CA-MLCK mice
DOI 10.1055/s-0034-1376086
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Nachweis in CareLit
Autor:innenO Inczefi, H Eutamene, M Leveque, C Bétoulières, R Róka, A Rosztóczy, T Wittmann, J Turner, V Theodorou, L Ferrier
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe05/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Elevated gut permeability is linked to visceral hypersensitivity in patients with IBS. Using transgenic mice that express constitutively-active myosin light chain kinase (CA-MLCK) specifically within the intestinal epithelium in this way having gut hyperpermeability, we aimed to evaluate the pattern of visceral sensitivity and to determine putative mechanisms under basal and stress conditions. Materials…
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Zitierempfehlung
O Inczefi, H Eutamene, M Leveque, C Bétoulières, R Róka, A Rosztóczy, T Wittmann, J Turner, V Theodorou, L Ferrier (2014) Visceral hyposensitivity induced by congenitally elevated gut permeability turns to hypersensitivity after stress in CA-MLCK mice. Zeitschrift für Gastroenterologie (05). https://doi.org/10.1055/s-0034-1376086
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