CareLit · DOI-Nachweis · Pneumologie
Sphingosine-1-phosphate receptor 4 (S1P4) deficiency does not alter Th2-induced pulmonary vascular hyperresponsiveness
DOI 10.1055/s-0034-1376382
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Tabeling, E Noe, N Suttorp, R Klopfleisch, M Witzenrath
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Pulmonary arterial hypertension (PAH) is characterized by increased vasoconstriction and pulmonary arterial remodeling leading to elevated pulmonary vascular resistance and right ventricular failure. Pulmonary Th2 inflammation induces morphologic and functional changes resembling PAH. Sphingosine-1-phosphate (S1P) signals via five G protein-coupled receptors (S1P1 – 5) thereby regulating a wide range o…
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Zitierempfehlung
C Tabeling, E Noe, N Suttorp, R Klopfleisch, M Witzenrath (2014) Sphingosine-1-phosphate receptor 4 (S1P4) deficiency does not alter Th2-induced pulmonary vascular hyperresponsiveness. Pneumologie (06). https://doi.org/10.1055/s-0034-1376382
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