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Species comparison of interleukin-13 induced airway hyperreactivity in precision-cut lung slices

O Danov, SM Jimenez Delgado, H Drake, S Schindler, O Pfennig, C Förster, A Braun, K Sewald · Pneumologie · Ausgabe 06/2014

DOI 10.1055/s-0034-1376770

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Autor:innenO Danov, SM Jimenez Delgado, H Drake, S Schindler, O Pfennig, C Förster, A Braun, K Sewald
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Interleukin-13 is a key cytokine of asthma and elevated in asthmatics resulting in airway hyperresponsiveness (AHR). AHR is a hallmark of allergic asthma defined as exaggerated bronchoconstriction in response to contractile stimuli. Research for the development of new drugs is mainly based on appropriate in vivo and in vitro models. There is a need for translational models with improved predictivity for human. For c…

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Zitierempfehlung

O Danov, SM Jimenez Delgado, H Drake, S Schindler, O Pfennig, C Förster, A Braun, K Sewald (2014) Species comparison of interleukin-13 induced airway hyperreactivity in precision-cut lung slices. Pneumologie (06). https://doi.org/10.1055/s-0034-1376770

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