CareLit · DOI-Nachweis · Pneumologie
RORγt-specific RNAi decreases allergic airway inflammation and airway hyperresponsiveness in a mouse model of neutrophilic asthma
DOI 10.1055/s-0034-1376774
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Autor:innenS Webering, L Lunding, J Behrends, H Fehrenbach, M Wegmann
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Recent studies suggest T helper 17 (Th17) cells as important players in the progression of asthma towards a severe phenotype. Characterized by the production of pro-inflammatory cytokines like TNF-α, IL-1ß, IL-22 and IL-17A, Th17 cells appear to act as general promoters of chronic inflammatory responses. These effector functions are regulated by the transcription factor Retinoic acid-related Orphan Rec…
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Zitierempfehlung
S Webering, L Lunding, J Behrends, H Fehrenbach, M Wegmann (2014) RORγt-specific RNAi decreases allergic airway inflammation and airway hyperresponsiveness in a mouse model of neutrophilic asthma. Pneumologie (06). https://doi.org/10.1055/s-0034-1376774
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