CareLit · DOI-Nachweis · Pneumologie
Peptide of alpha1-antitrypsin: potential novel therapy
DOI 10.1055/s-0034-1376776
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Nachweis in CareLit
Autor:innenS Wrenger, T Welte, S Janciauskiene
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: We confirmed that alpha1-antitrypsin (A1AT) exhibits immunomodulatory activities that are unrelated to inhibition of neutrophil elastase. A1AT does not suppress but rather modulates production of pro- and anti-inflammatory substances, dependent on the cell/tissue response magnitude (output) to pro-inflammatory stimuli. A1AT down-regulates a hyper-immunity or hyper-inflammation without impairing the norma…
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Zitierempfehlung
S Wrenger, T Welte, S Janciauskiene (2014) Peptide of alpha1-antitrypsin: potential novel therapy. Pneumologie (06). https://doi.org/10.1055/s-0034-1376776
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