CareLit · DOI-Nachweis · Pneumologie
Evaluation of small molecule FRET reporter for the diagnosis and monitoring of proteolytic activity in a chronic obstructive lung disease model
DOI 10.1055/s-0034-1376783
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Autor:innenG Reither, N Heath, O Holz, N Kahn, J Hohlfeld, C Schultz, MA Mall
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Proteases such as neutrophil elastase (NE) and matrix metalloprotease 12 (MMP-12) are key factors in inflammatory processes and contribute the gradual destruction of extracellular lung matrix in chronic inflammation. We now hypothesize that activity levels of inflammation-relevant proteases may be useful indicators for the onset and progression of obstructive lung diseases such as cystic fibrosis or COPD. With the r…
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Zitierempfehlung
G Reither, N Heath, O Holz, N Kahn, J Hohlfeld, C Schultz, MA Mall (2014) Evaluation of small molecule FRET reporter for the diagnosis and monitoring of proteolytic activity in a chronic obstructive lung disease model. Pneumologie (06). https://doi.org/10.1055/s-0034-1376783
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