CareLit · DOI-Nachweis · Pneumologie
Silencing of miR-148b ameliorates cystic fibrosis-like lung diseases in βENaC-overexpressing mice
DOI 10.1055/s-0034-1376785
Bibliografische Angaben
Nachweis in CareLit
Autor:innenR Agrawal, M Castoldi, S Altamura, F Stanke, M Meister, T Muley, CM Greene, B Tümmler, MU Muckenthaler, MA Mall
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
MicroRNAs are involved in diverse biological and pathological processes. Here, we studied the potential role of miRNAs in the in vivo pathogenesis of cystic fibrosis (CF)-like lung disease in βENaC-overexpressing (βENaC-Tg) mice. We performed miRNA array analysis in lung tissue of βENaC-Tg and wild-type mice. Differentially expressed miRNAs were validated by qRT-PCR and their target genes were identified by bioinfor…
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Zitierempfehlung
R Agrawal, M Castoldi, S Altamura, F Stanke, M Meister, T Muley, CM Greene, B Tümmler, MU Muckenthaler, MA Mall (2014) Silencing of miR-148b ameliorates cystic fibrosis-like lung diseases in βENaC-overexpressing mice. Pneumologie (06). https://doi.org/10.1055/s-0034-1376785
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