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Rescue of function in a cystic fibrosis mouse model by transfer of hematopoetic stem cells

A Munder, R Struß, A Schambach, B Tümmler · Pneumologie · Ausgabe 06/2014

DOI 10.1055/s-0034-1376787

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Autor:innenA Munder, R Struß, A Schambach, B Tümmler
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Cystic fibrosis (CF) is the most common hereditary disease in the Caucasian population. The disease causing gene CFTR was identified in 1989. So far, more than 1,800 mutations have been identified in the CFTR gene [1], which codes for a cyclic adenosine monophosphate-regulated chloride channel. The malfunction of this channel leads to a progressive loss of function in the CF lung, which is the decisive factor for mo…

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A Munder, R Struß, A Schambach, B Tümmler (2014) Rescue of function in a cystic fibrosis mouse model by transfer of hematopoetic stem cells. Pneumologie (06). https://doi.org/10.1055/s-0034-1376787

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