CareLit · DOI-Nachweis · Pneumologie
Downregulation of Hemeoxygenase-1 and Altered Cellular Homeostasis in Cystic Fibrosis
DOI 10.1055/s-0034-1376792
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Autor:innenSP Chillappagari, S Venkatesan, V Garapati, P Mahavadi, A Munder, A Seubert, A Guenther, B Schmeck, B Tümmler, M Henke
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Hemeoxygenase-1 (HO-1), an inducible heat shock protein, is upregulated in response to multiple cellular insults via oxidative stress, lipopolysaccharides (LPS), and hypoxia. In this study, we investigated the role of toll-like receptor 4 (TLR4), hypoxia-inducible factor-1α (HIF-1α) and iron on HO-1 expression in cystic fibrosis (CF). Immunohistochemical analysis of TLR4, HO-1, ferritin and HIF-1α were performed on…
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Zitierempfehlung
SP Chillappagari, S Venkatesan, V Garapati, P Mahavadi, A Munder, A Seubert, A Guenther, B Schmeck, B Tümmler, M Henke (2014) Downregulation of Hemeoxygenase-1 and Altered Cellular Homeostasis in Cystic Fibrosis. Pneumologie (06). https://doi.org/10.1055/s-0034-1376792
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