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Influenza virus impairs fibroblast growth factor receptor 2b dependent epithelial regeneration from a distal airway epithelial progenitor pool

J Quantius, C Schmoldt, K Hoegner, E El Agha, W Seeger, J Lohmeyer, S Bellusci, S Herold · Pneumologie · Ausgabe 06/2014

DOI 10.1055/s-0034-1376793

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Autor:innenJ Quantius, C Schmoldt, K Hoegner, E El Agha, W Seeger, J Lohmeyer, S Bellusci, S Herold
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

IV (influenza virus) pneumonia is associated with apoptotic damage of the alveolar epithelial barrier and therefore efficient alveolar repair is crucial for recovery. Lineage tracing studies suggest that the adult lung contains epithelial progenitor cells which proliferate after injury. Fibroblast growth factor 10 (FGF10) plays a major role in lung development and is also known to have reparative, anti-apoptotic pot…

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Zitierempfehlung

J Quantius, C Schmoldt, K Hoegner, E El Agha, W Seeger, J Lohmeyer, S Bellusci, S Herold (2014) Influenza virus impairs fibroblast growth factor receptor 2b dependent epithelial regeneration from a distal airway epithelial progenitor pool. Pneumologie (06). https://doi.org/10.1055/s-0034-1376793

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