CareLit · DOI-Nachweis · Pneumologie
Role of arginase 1 in lung protective immunity against Streptococcus pneumoniae in mice
DOI 10.1055/s-0034-1376796
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Autor:innenS Knippenberg, C Brumshagen, F Aschenbrenner, T Welte, UA Maus
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Type 2 helper cell (TH2) dominated chronic lung diseases like asthma are associated with an increased risk for bacterial lung infections. However, the underlying mechanisms are poorly defined. Arginase 1 has been suggested to play an important role in the pathophysiology of asthma, and is rapidly induced in lung macrophages by TH2 cytokines, thereby limiting macrophage-derived antimicrobial nitric oxide (NO) product…
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Zitierempfehlung
S Knippenberg, C Brumshagen, F Aschenbrenner, T Welte, UA Maus (2014) Role of arginase 1 in lung protective immunity against Streptococcus pneumoniae in mice. Pneumologie (06). https://doi.org/10.1055/s-0034-1376796
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