CareLit · DOI-Nachweis · Pneumologie
Inhibition of profibrotic signaling in fibroblasts from patients with idiopathic pulmonary fibrosis by histone deacetylase-inhibitors or pirfenidone
DOI 10.1055/s-0034-1376798
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Nachweis in CareLit
Autor:innenM Korfei, S Skwarna, I Henneke, O Klymenko, G Dahlem, S Ziegler, D von der Beck, W Klepetko, L Fink, W Seeger, O Krämer, A Guenther
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Introduction: Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by distorted pulmonary structure and the excessive deposition of extracellular matrix (ECM) proteins, such as collagen. Myofibroblasts are the primary collagen-producing cells in IPF lungs, and their accumulation within pathologic lesions called fibroblast foci (FF) is a hallmark of IPF. To explore new drugs for IPF, we investigated t…
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Zitierempfehlung
M Korfei, S Skwarna, I Henneke, O Klymenko, G Dahlem, S Ziegler, D von der Beck, W Klepetko, L Fink, W Seeger, O Krämer, A Guenther (2014) Inhibition of profibrotic signaling in fibroblasts from patients with idiopathic pulmonary fibrosis by histone deacetylase-inhibitors or pirfenidone. Pneumologie (06). https://doi.org/10.1055/s-0034-1376798
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