CareLit · DOI-Nachweis · Pneumologie
Endogenous Fgfr2b ligands are dispensable for fibrosis formation and resolution in bleomycin-injured mice
DOI 10.1055/s-0034-1376802
Bibliografische Angaben
Nachweis in CareLit
Autor:innenB MacKenzie, D Al Alam, I Henneke, E El Agha, J Quantius, CM Chao, J Wilhelm, M Königshoff, S Herold, W Klepetko, A Günther, W Seeger, S Bellusci
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Increased fibroblast growth factor 10 (Fgf10) expression in vivo and administration of exogenous FGF7 recombinant protein enhance lung repair due to bleomycin injury by sending survival signals to lung epithelial cells via tyrosine kinase fibroblast growth factor receptor 2b (Fgfr2b). Given the therapeutic effects of these ligands during bleomycin injury, we hypothesized that activation of the Fgfr2b endogenous path…
Zitieren
Zitierempfehlung
B MacKenzie, D Al Alam, I Henneke, E El Agha, J Quantius, CM Chao, J Wilhelm, M Königshoff, S Herold, W Klepetko, A Günther, W Seeger, S Bellusci (2014) Endogenous Fgfr2b ligands are dispensable for fibrosis formation and resolution in bleomycin-injured mice. Pneumologie (06). https://doi.org/10.1055/s-0034-1376802
Mit CareLit weiterarbeiten