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Role of Bcl-xL in hepatocyte growth factor-elicited epithelial protection in idiopathic pulmonary fibrosis

S Skwarna, I Henneke, W Seeger, T Geiser, A Günther, C Ruppert · Pneumologie · Ausgabe 06/2014

DOI 10.1055/s-0034-1376808

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Autor:innenS Skwarna, I Henneke, W Seeger, T Geiser, A Günther, C Ruppert
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Hepatocyte growth factor (HGF) is a cytokine with pleiotropic functions during wound healing and repair. Its anti-fibrotic effects were shown in animal models of lung fibrosis and linked to improved cellular survival and proliferation and reduced myofibroblast accumulation. HGF-elicited, pro-survival pathways have yet not been investigated in detail in lung epithelial cells. Based on literature, our study is focused…

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Zitierempfehlung

S Skwarna, I Henneke, W Seeger, T Geiser, A Günther, C Ruppert (2014) Role of Bcl-xL in hepatocyte growth factor-elicited epithelial protection in idiopathic pulmonary fibrosis. Pneumologie (06). https://doi.org/10.1055/s-0034-1376808

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