CareLit · DOI-Nachweis · Pneumologie
Wnt-Heparan Sulfate Proteoglycan interaction in fibrotic lung disease
DOI 10.1055/s-0034-1376810
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Autor:innenS Vierkotten, V Aumiller, F Uhl, M Königshoff
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of yet unknown etiology. Recently, (re)activation of developmental pathways, such as Wnt/β-catenin in the alveolar epithelium has been linked to disease development. Regulation of Wnt/β-catenin activation has been shown to be dependent on Heparan Sulfate Proteoglycans (HSPGs). The role of Wnt-HSPG interaction in IPF, however, remains to be el…
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Zitierempfehlung
S Vierkotten, V Aumiller, F Uhl, M Königshoff (2014) Wnt-Heparan Sulfate Proteoglycan interaction in fibrotic lung disease. Pneumologie (06). https://doi.org/10.1055/s-0034-1376810
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