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Novel alveolar epithelial cell differentiation markers in lung injury and repair

K Mutze, F Uhl, J Milosevic, O Eickelberg, M Königshoff · Pneumologie · Ausgabe 06/2014

DOI 10.1055/s-0034-1376811

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Nachweis in CareLit

Autor:innenK Mutze, F Uhl, J Milosevic, O Eickelberg, M Königshoff
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Objective: The alveolar epithelium, consisting of mainly alveolar epithelial type 1 (AT1) and type 2 (AT2) cells, represents a major site of tissue destruction in idiopathic pulmonary fibrosis. Several studies indicate that adult AT2 cells are able to self-renew and exert progenitor function for AT1 cells upon alveolar injury in vivo. However, cell differentiation pathways enabling this plasticity are poorly underst…

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Zitierempfehlung

K Mutze, F Uhl, J Milosevic, O Eickelberg, M Königshoff (2014) Novel alveolar epithelial cell differentiation markers in lung injury and repair. Pneumologie (06). https://doi.org/10.1055/s-0034-1376811

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