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In vivo effects of TGF-β1 in lung surfactant regulation, lung meachanics amd structure

E Lopez-Rodriguez, C Boden, S Knippenberg, A Pascual, J Perez-Gil, M Kolb, J Gauldie, U Maus, M Ochs, L Knudsen · Pneumologie · Ausgabe 06/2014

DOI 10.1055/s-0034-1376812

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Autor:innenE Lopez-Rodriguez, C Boden, S Knippenberg, A Pascual, J Perez-Gil, M Kolb, J Gauldie, U Maus, M Ochs, L Knudsen
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Transforming growth factor beta 1 (TGF-β1) is a signalling protein with a wide range of biological activities. TGF-β1 is thought to have a pivotal role in fibrogenesis, where TGF-β1 induces myofibroblast migration and increases extracellular matrix synthesis, including collagen. Moreover, it has been described that TGF-β1 is a negative modulator of the regulation of surfactant associated proteins A (SP-A), B (SP-B)…

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E Lopez-Rodriguez, C Boden, S Knippenberg, A Pascual, J Perez-Gil, M Kolb, J Gauldie, U Maus, M Ochs, L Knudsen (2014) In vivo effects of TGF-β1 in lung surfactant regulation, lung meachanics amd structure. Pneumologie (06). https://doi.org/10.1055/s-0034-1376812

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