CareLit · DOI-Nachweis · Pneumologie
Interleukin 18 in the pathogenesis of experimental bronchiolitis obliterans syndrome (BOS)
DOI 10.1055/s-0034-1376820
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Nachweis in CareLit
Autor:innenA Zakrzewicz, L Rabin, A Fischer, W Padberg, V Grau
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Bronchiolitis obliterans syndrome (BOS), characterized by bronchiolitis obliterans, vascular remodeling and general fibrosis is a major cause of mortality after lung transplantation. Elevated levels of IFNγ-dependent chemokines are predictive factors for the development of BOS. IFNγ expression can be induced by IL18, a pro-inflammatory cytokine, secreted mainly by macrophages upon inflammasome activati…
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Zitierempfehlung
A Zakrzewicz, L Rabin, A Fischer, W Padberg, V Grau (2014) Interleukin 18 in the pathogenesis of experimental bronchiolitis obliterans syndrome (BOS). Pneumologie (06). https://doi.org/10.1055/s-0034-1376820
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