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Generation of a NKX2.1 knockin human induced pluripotent stem cell reporter line for monitoring the generation of respiratory cells

S Weinreich, R Haller, S Ulrich, C Mauritz, U Martin · Pneumologie · Ausgabe 06/2014

DOI 10.1055/s-0034-1376822

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Autor:innenS Weinreich, R Haller, S Ulrich, C Mauritz, U Martin
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

One promising therapeutic option to cure hereditary pulmonary diseases like cystic fibrosis might be a cell replacement therapy comprising the generation of patient specific autologous induced pluripotent stem cells (iPSCs), followed by the correction of the genetic mutation, differentiation into the needed airway cell type and replacement of the endogenous cells. For long term restoration, most likely airway progen…

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S Weinreich, R Haller, S Ulrich, C Mauritz, U Martin (2014) Generation of a NKX2.1 knockin human induced pluripotent stem cell reporter line for monitoring the generation of respiratory cells. Pneumologie (06). https://doi.org/10.1055/s-0034-1376822

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