CareLit · DOI-Nachweis · Pneumologie
Changes in local alpha-1-antitrypsin expression during the pathogenesis of experimental bronchiolitis obliterans syndrome
DOI 10.1055/s-0034-1376823
Bibliografische Angaben
Nachweis in CareLit
Autor:innenK Siebers, S Atanasova, M Reichert, W Padberg, V Grau
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Alpha-1-antitrypsin (AAT) is the prototypical member of the serin protease inhibitor (SERPIN) family. It is mainly produced by the liver, but can also be produced by monocytes, macrophages and alveolar epithelial cells. AAT is released in large amounts during the acute phase of inflammation and limits tissue damage due to its antiprotease activity. Anti-inflammatory effects independent of antiprotease function are c…
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Zitierempfehlung
K Siebers, S Atanasova, M Reichert, W Padberg, V Grau (2014) Changes in local alpha-1-antitrypsin expression during the pathogenesis of experimental bronchiolitis obliterans syndrome. Pneumologie (06). https://doi.org/10.1055/s-0034-1376823
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