CareLit · DOI-Nachweis · Pneumologie
Generation of CF-patient derived iPS cells and efficient footprintless designer nuclease-based gene targeting
DOI 10.1055/s-0034-1376851
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Merkert, S Wunderlich, C Bednarski, A Haase, AK Dreyer, K Schwanke, T Cathomen, U Martin
ZeitschriftPneumologie
Ausgabe06/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
*Presenting author The ability to genetically modify human induced pluripotent stem cells (hiPSCs), including the correction of gene defects by means of homologous recombination (HR) is of great interest regarding their potential for ex vivo gene therapy, especially in terms of rare pulmonary diseases like Cystic Fibrosis (CF). Genetic engineering of hiPSCs via customized designer nucleases has been shown to be sign…
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Zitierempfehlung
S Merkert, S Wunderlich, C Bednarski, A Haase, AK Dreyer, K Schwanke, T Cathomen, U Martin (2014) Generation of CF-patient derived iPS cells and efficient footprintless designer nuclease-based gene targeting. Pneumologie (06). https://doi.org/10.1055/s-0034-1376851
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