CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Autoantibodies to glycoprotein 2 are associated with the clinical phenotype in Crohn's disease
DOI 10.1055/s-0034-1385987
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Autor:innenD Roggenbuck, DP Bogdanos, D Reinhold, U von Arnim, P Malfertheiner, A Forbes, K Conrad, M Laaß
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Pancreatic antibodies (PAB) recognize zymogen granule glycoprotein 2 (GP2) as major autoantigenic target in patients with Crohn's disease (CD). Expression of GP2 has been demonstrated at the site of intestinal inflammation, explaining the previously unaddressed contradiction of pancreatic autoimmunity and intestinal inflammation. GP2 is a specific receptor on microfold (M) cells of intestinal Peyer's pat…
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Zitierempfehlung
D Roggenbuck, DP Bogdanos, D Reinhold, U von Arnim, P Malfertheiner, A Forbes, K Conrad, M Laaß (2014) Autoantibodies to glycoprotein 2 are associated with the clinical phenotype in Crohn's disease. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0034-1385987
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