CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
TLR-activated monocytes express IFN-lambda receptor 1 and trigger IFN-gamma secretion of NK cells after stimulation with IFN-lambda
DOI 10.1055/s-0034-1386089
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Nachweis in CareLit
Autor:innenB Krämer, BS Sastre Turrión, A Glässner, F Wolter, P Kokordelis, M Eisenhardt, HD Nischalke, CP Strassburg, U Spengler, J Nattermann
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2014
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Immungenetic data suggest that lambda-IFNs (l-IFN) may modulate anti-HCV activity of natural killer (NK) cells. However, NK cells do not express the IFN-lambda receptor 1 (IFN-lR1). Thus, we studied the hypothesis that l-IFNs act on other leucocyte subsets, which then indirectly modulate NK cell activity. Methods: IFN-lR1 expression was studied by flowcytometry on circulating leukocyte subsets in healthy…
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Zitierempfehlung
B Krämer, BS Sastre Turrión, A Glässner, F Wolter, P Kokordelis, M Eisenhardt, HD Nischalke, CP Strassburg, U Spengler, J Nattermann (2014) TLR-activated monocytes express IFN-lambda receptor 1 and trigger IFN-gamma secretion of NK cells after stimulation with IFN-lambda. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0034-1386089
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