CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Extrahepatic manifestations of ATP-binding cassette transporter B4 (ABCB4) deficiency detected in a systematic phenomics platform
DOI 10.1055/s-0034-1386109
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Autor:innenK Hochrath, M Krawczyk, M Hrabĕ de Angelis, F Lammert
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2014
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: The ABCB4 gene encodes the hepatocanalicular phospholipid floppase, which translocates phosphatidylcholine from liver into bile. Abcb4 knockout (Abcb4 -/-) mice develop chronic cholangitis and biliary fibrosis similar to primary sclerosing cholangitis in humans (Gastroenterology 2004;127:261 – 74). To date, the interactions of these diseases with extrahepatic organs are not fully defined. With the aim to…
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Zitierempfehlung
K Hochrath, M Krawczyk, M Hrabĕ de Angelis, F Lammert (2014) Extrahepatic manifestations of ATP-binding cassette transporter B4 (ABCB4) deficiency detected in a systematic phenomics platform. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0034-1386109
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