CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Nutritional α-amylase/trypsin inhibitors (ATIs) promote macrophage infiltration into liver associated with increased expression of the endocannabinoid 1 receptor (eCBr-1)
DOI 10.1055/s-0034-1386113
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Autor:innenJM Laparra Llopis, D Schuppan
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Gluten proteins (gliadin) trigger celiac disease (CD) involving innate and adaptive immunity. CD has been found in about 3.5% of patients with non-alcoholic fatty liver disease (NAFLD). We recently identified wheat ATIs (i.e., CM3 and 0.19) as strong activators of innate immune response(s) via toll like receptor (TLR)-4. eCBr-1(-/-) mice and pharmacological blockade of they abolished LPS-induced TLR4-m…
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Zitierempfehlung
JM Laparra Llopis, D Schuppan (2014) Nutritional α-amylase/trypsin inhibitors (ATIs) promote macrophage infiltration into liver associated with increased expression of the endocannabinoid 1 receptor (eCBr-1). Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0034-1386113
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