CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Human ex vivo models to analyze combinations and immunostimulatory effects induced by oncolytic viruses
DOI 10.1055/s-0034-1386209
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Autor:innenB Heinrich, M Delic, K Goepfert, C Breitbach, C Dinsart, J Rommelaere, PR Galle, M Moehler
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Oncolytic viruses offer an interesting approach not only to kill cancer cells but also to stimulate the human immune system by tumor cell lysates (TCL). Herein, the oncolytic parvovirus H-1 (H-1PV) presents clear immunostimulatory features. Combination of oncolytic viruses with chemotherapy-based regimes or with immune-checkpoint inhibitors, e.g. the anti-CTLA-4 antibody tremelimumab, are strategies to…
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Zitierempfehlung
B Heinrich, M Delic, K Goepfert, C Breitbach, C Dinsart, J Rommelaere, PR Galle, M Moehler (2014) Human ex vivo models to analyze combinations and immunostimulatory effects induced by oncolytic viruses. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0034-1386209
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