CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
The extracellular proteinase Expi/Wfdc18 is overexpressed in various murine cancers and represents an animal model for HE4/WFDC2 overexpression in human tumours
DOI 10.1055/s-0034-1386211
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Nachweis in CareLit
Autor:innenR Liebe, R Hall, T Deduliana, E Burgermeister, M Ebert, F Lammert, S Dooley
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe08/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Recently we have investigated quantitative trait loci (QTLs) that determine susceptibility to TGF-beta signalling in mouse hepatocytes in vitro (Liebe et al. Physiol Genomics 2013). Expi/Wfdc18 candidacy was identified by eQTL and DNA variant analyses. We availed of a knockout mouse to assess a potential role in experimental fibrosis, and Expi/Wfdc18 knockouts showed decreased hepatic collagen contents…
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Zitierempfehlung
R Liebe, R Hall, T Deduliana, E Burgermeister, M Ebert, F Lammert, S Dooley (2014) The extracellular proteinase Expi/Wfdc18 is overexpressed in various murine cancers and represents an animal model for HE4/WFDC2 overexpression in human tumours. Zeitschrift für Gastroenterologie (08). https://doi.org/10.1055/s-0034-1386211
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