CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
Homocysteine-Thiolactone links metabolic stress to ovarian function by regulating steroid biosynthesis and receptor expression
DOI 10.1055/s-0034-1387979
Bibliografische Angaben
Nachweis in CareLit
Autor:innenS Heublein, S Hecht, R Pavlik, U Noss, T Vrekoussis, U Jeschke, CJ Thaler
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe09/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Elevated homocysteine leads to increased levels of homocysteine thiolactone (HCTL), a highly active thioester that alters protein structure and function by N-homocysteinylation. The most common causes for elevated homocysteine/HCTL are malnutrition and MTHFR mutations. Having reported that the 677 C >T MTHFR mutation is associated with poor ovarian response in patients undergoing controlled ovarian sti…
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Zitierempfehlung
S Heublein, S Hecht, R Pavlik, U Noss, T Vrekoussis, U Jeschke, CJ Thaler (2014) Homocysteine-Thiolactone links metabolic stress to ovarian function by regulating steroid biosynthesis and receptor expression. Geburtshilfe und Frauenheilkunde (09). https://doi.org/10.1055/s-0034-1387979
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