CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
Evaluation of the covalently linked antimetabolite 5-FdU with alendronate in a preclinical breast cancer bone metastases mouse model
DOI 10.1055/s-0034-1388339
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Schem, R Tower, P Kneissl, AC Rambow, G Campbell, T Heilmann, W Jonat, CC Glüer, C Sohn, S Schott, S Tiwari
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe09/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Patients diagnosed with breast cancer in advanced tumor stages show a high frequency of skeletal metastases. These bone lesions uncouple the balance between bone formation and resorption, resulting in severe osteolysis. These lesions often result in increased fracture risk, compression of the spine and hypercalmia, decreasing the quality of life for the patient. As a result, anti-cancer chemotherapeutics are often c…
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Zitierempfehlung
C Schem, R Tower, P Kneissl, AC Rambow, G Campbell, T Heilmann, W Jonat, CC Glüer, C Sohn, S Schott, S Tiwari (2014) Evaluation of the covalently linked antimetabolite 5-FdU with alendronate in a preclinical breast cancer bone metastases mouse model. Geburtshilfe und Frauenheilkunde (09). https://doi.org/10.1055/s-0034-1388339
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