CareLit · DOI-Nachweis · Geburtshilfe und Frauenheilkunde
DNA double-strand break (DSB) repair analysis in epithelial mesenchymal transition cells (EMTs) derived from breast cancer specimens identifies new prognostic markers
DOI 10.1055/s-0034-1388413
Bibliografische Angaben
Nachweis in CareLit
Autor:innenT Gundelach, M Deniz, J Kaufmann, M Keimling, W Janni, L Wiesmüller
ZeitschriftGeburtshilfe und Frauenheilkunde
Ausgabe09/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: All currently known breast cancer susceptibility genes are linked to DSB repair. To find novel markers for breast cancer risk, we analyzed DSB repair in peripheral blood lymphocytes (PBLs) from high-risk individuals and revealed highly significant increases of error-prone mechanisms such as non-homologous end joining (NHEJ). To additionally capture non-hereditary factors as potential prognostic markers,…
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Zitierempfehlung
T Gundelach, M Deniz, J Kaufmann, M Keimling, W Janni, L Wiesmüller (2014) DNA double-strand break (DSB) repair analysis in epithelial mesenchymal transition cells (EMTs) derived from breast cancer specimens identifies new prognostic markers. Geburtshilfe und Frauenheilkunde (09). https://doi.org/10.1055/s-0034-1388413
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