CareLit · DOI-Nachweis · Klinische Pädiatrie
Phase I/II trial vorinostat in children with relapsed malignancies: interim analysis report
DOI 10.1055/s-0034-1393940
Bibliografische Angaben
Nachweis in CareLit
Autor:innenO Witt, J Burhenne, R Witt, T Milde, C van Tilburg, A Seitz, JP Schenk, A Eisenmenger, U Abel, I Karapanagiotou-Schenkel
ZeitschriftKlinische Pädiatrie
Ausgabe12/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Histone deacetylases (HDACs) are key enzymes controlling epigenetic and cytoplasmatic signalling pathways involved in apoptosis, differentiation, cell cycle control and drug resistance. Our group has previously shown that single members of the HDAC family 1 – 11harbor important functions in pediatric pre-clinical neuronal cancer models and are highly expressed in a pediatrictumor samples. In this multi…
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Zitierempfehlung
O Witt, J Burhenne, R Witt, T Milde, C van Tilburg, A Seitz, JP Schenk, A Eisenmenger, U Abel, I Karapanagiotou-Schenkel (2014) Phase I/II trial vorinostat in children with relapsed malignancies: interim analysis report. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0034-1393940
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