CareLit · DOI-Nachweis · Klinische Pädiatrie
Targeting class I histone deacetylases in high risk medulloblastoma – analysis of molecular mechanisms and translational implications
DOI 10.1055/s-0034-1393941
Bibliografische Angaben
Nachweis in CareLit
Autor:innenJ Ecker, I Oehme, R Mazitschek, A Korshunov, M Kool, M Lodrini, HE Deubzer, A von Deimling, AE Kulozik, S Pfister, O Witt, T Milde
ZeitschriftKlinische Pädiatrie
Ausgabe12/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Introduction: Medulloblastoma (MB) is the most frequent pediatric malignant brain tumor. Four molecular subgroups with distinct genetic and epigenetic backgrounds as well as clinical characteristics have been identified. Especially in patients with Group 3 tumors overall survival remains poor despite aggressive multimodal treatment. We and others have previously shown that targeting MB tumors with histone deacetylas…
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Zitierempfehlung
J Ecker, I Oehme, R Mazitschek, A Korshunov, M Kool, M Lodrini, HE Deubzer, A von Deimling, AE Kulozik, S Pfister, O Witt, T Milde (2014) Targeting class I histone deacetylases in high risk medulloblastoma – analysis of molecular mechanisms and translational implications. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0034-1393941
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