CareLit · DOI-Nachweis · Klinische Pädiatrie
Cell surface metalloproteases as targets in glioblastoma: implications for tumor growth and therapy resistance
DOI 10.1055/s-0034-1393942
Bibliografische Angaben
Nachweis in CareLit
Autor:innenF Dong, M Eibach, U Schlomann, C Conrad, C Nimsky, H Strik, A Pagenstecher, JW Bartsch
ZeitschriftKlinische Pädiatrie
Ausgabe12/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Despite multimodal therapy, Glioblastoma (GBM) chemotherapy with Temozolomide (TMZ) remains inefficient due to chemoresistance. MMP and ADAM metalloproteases (MPs) are increased in GBM and could contribute to chemoresistance and TMZ induced recurrence of glioblastoma. Methods: TMZ sensitivity of GBM cells was assessed with MP inhibitors batimastat (BB-94) and marimastat (BB-2516). Induction of MPs by TMZ…
Zitieren
Zitierempfehlung
F Dong, M Eibach, U Schlomann, C Conrad, C Nimsky, H Strik, A Pagenstecher, JW Bartsch (2014) Cell surface metalloproteases as targets in glioblastoma: implications for tumor growth and therapy resistance. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0034-1393942
Mit CareLit weiterarbeiten