CareLit · DOI-Nachweis · Klinische Pädiatrie
HDAC10: a novel drug target for childhood tumors of the nervous system
DOI 10.1055/s-0034-1393944
Bibliografische Angaben
Nachweis in CareLit
Autor:innenE Koeneke, P Arnaiz, O Witt, I Oehme
ZeitschriftKlinische Pädiatrie
Ausgabe12/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
The histone deacetylase (HDAC) family is comprised of diverse enzymes that are divided into different classes and are involved in many cellular processes, very often linked to tumor biology. Here, we introduce the class IIb enzyme HDAC10 as a potential drug target for the treatment of childhood tumors of the nervous system, such as medulloblastoma. The evolutionarily highly conserved process of autophagy helps aggre…
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Zitierempfehlung
E Koeneke, P Arnaiz, O Witt, I Oehme (2014) HDAC10: a novel drug target for childhood tumors of the nervous system. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0034-1393944
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