CareLit · DOI-Nachweis · Klinische Pädiatrie
Smac mimetic promotes glioblastoma cancer stem-like cell differentiation by activating NF-κB
DOI 10.1055/s-0034-1393946
Bibliografische Angaben
Nachweis in CareLit
Autor:innenA Tchoghandjian, C Jennewein, I Eckhardt, S Momma, D Figarella-Branger, S Fulda
ZeitschriftKlinische Pädiatrie
Ausgabe12/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Recently, a broader role of inhibitor of apoptosis (IAP) proteins besides their antiapoptotic functions has been described. Therefore, we investigated the effect of non-toxic concentrations of the small-molecule Smac mimetic BV6, which antagonizes IAP proteins, on differentiation of cancer stem-like cells (CSLCs) derived from primary glioblastoma (GBM) specimens. Here, we identify a novel function of BV6 in regulati…
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Zitierempfehlung
A Tchoghandjian, C Jennewein, I Eckhardt, S Momma, D Figarella-Branger, S Fulda (2014) Smac mimetic promotes glioblastoma cancer stem-like cell differentiation by activating NF-κB. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0034-1393946
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