CareLit · DOI-Nachweis · Klinische Pädiatrie
Treatment approaches combining cytostatic drugs with the oncolytic parvovirus H-1 increase cytotoxic effects in cell culture models of highly malignant pediatric brain tumors
DOI 10.1055/s-0034-1393947
Bibliografische Angaben
Nachweis in CareLit
Autor:innenC Westphal, S Öztürk, R Josupeit, B Leuchs, O Witt, J Rommelaere, J Lacroix
ZeitschriftKlinische Pädiatrie
Ausgabe12/2014
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Oncolytic virotherapy with Parvovirus H-1 (H-1PV) represents a new therapeutic approach investigated in a phase I/IIa clinical trial recruiting adult glioblastoma patients. In pediatric neurooncology there is also an urgent need for new therapeutic options. In vitro H-1PV has already been demonstrated to induce cytotoxic effects in medulloblastoma and pediatric glioblastoma. However, the application of combination t…
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Zitierempfehlung
C Westphal, S Öztürk, R Josupeit, B Leuchs, O Witt, J Rommelaere, J Lacroix (2014) Treatment approaches combining cytostatic drugs with the oncolytic parvovirus H-1 increase cytotoxic effects in cell culture models of highly malignant pediatric brain tumors. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0034-1393947
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