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Molecular genetic analysis of thirty-five diffuse high-grade astrocytomas in children < 3 years of age defines a distinct infant HGG entity

GH Gielen, M Gessi, FR Buttarelli, C Baldi, J Hammes, A zur Muehlen, E Doerner, F Giangaspero, AO von Bueren, CM Kramm, A Waha, T Pietsch · Klinische Pädiatrie · Ausgabe 12/2014

DOI 10.1055/s-0034-1393948

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Autor:innenGH Gielen, M Gessi, FR Buttarelli, C Baldi, J Hammes, A zur Muehlen, E Doerner, F Giangaspero, AO von Bueren, CM Kramm, A Waha, T Pietsch
ZeitschriftKlinische Pädiatrie
Ausgabe12/2014
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

Pediatric high-grade gliomas (pHGG) are considered to differ from adult HGG in their pathogenesis and biological behaviour. However, few cases of infants have been analyzed so far. We studied the molecular features in a cohort of 35 infants with diffuse high-grade astrocytomas (8 anaplastic astrocytomas (WHO grade III) and 27 glioblastomas (WHO grade IV)) by immunohistochemistry, multiplex ligation probe-dependent a…

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Zitierempfehlung

GH Gielen, M Gessi, FR Buttarelli, C Baldi, J Hammes, A zur Muehlen, E Doerner, F Giangaspero, AO von Bueren, CM Kramm, A Waha, T Pietsch (2014) Molecular genetic analysis of thirty-five diffuse high-grade astrocytomas in children < 3 years of age defines a distinct infant HGG entity. Klinische Pädiatrie (12). https://doi.org/10.1055/s-0034-1393948

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