CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Cholestasis and bile acids induce expression of the oncofetal marker Nope in adult murine hepatocytes independent of Fxr
DOI 10.1055/s-0034-1397048
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Nachweis in CareLit
Autor:innenA Bowe, V Hoffmann, CH Morton, P Fickert, D Nierhoff
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Neighbor of Punc E11 (Nope) is strongly expressed in hepatic stem/progenitor cells and in hepatocellular carcinoma but not in terminally differentiated hepatocytes. We here investigated the expression pattern of Nope in adult mice after biliary liver injury. Methods: Liver tissue was extracted from adult C57Bl/6 mice and Fxr-/- mice 24 hours up to 4 weeks after bile duct ligation (BDL) or after a 1 week…
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Zitierempfehlung
A Bowe, V Hoffmann, CH Morton, P Fickert, D Nierhoff (2015) Cholestasis and bile acids induce expression of the oncofetal marker Nope in adult murine hepatocytes independent of Fxr. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397048
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