CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Comparative analysis of C5aR and C5L2 receptor deficiency in liver and kidney fibrosis
DOI 10.1055/s-0034-1397049
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Autor:innenIV Martin, P Boor, T Ostendorf, J Floege, F Lammert, SN Weber
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: Complement factor C5a has two known receptors, C5aR and C5L2. C5aR is involved in transduction of the proinflammatory effects of C5a, whereas C5L2 has been suggested as a decoy receptor. We previously demonstrated a pro-fibrotic role of C5a and C5aR in kidney and liver, but nothing is known concerning the potential involvement of C5L2 in organ fibrosis. Methods: C5aR-/-, C5L2-/- and wild-type (WT) contro…
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Zitierempfehlung
IV Martin, P Boor, T Ostendorf, J Floege, F Lammert, SN Weber (2015) Comparative analysis of C5aR and C5L2 receptor deficiency in liver and kidney fibrosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397049
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