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Fibroblast growth factor 7 inhibits hepatic steatosis, inflammation and fibrosis in murine models of on non-alcoholic steatohepatitis

B Czech, D Valletta, T Amann, A Bosserhoff, C Hellerbrand · Zeitschrift für Gastroenterologie · Ausgabe 01/2015

DOI 10.1055/s-0034-1397059

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Autor:innenB Czech, D Valletta, T Amann, A Bosserhoff, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben

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Abstract-Vorschau

The activation of hepatic stellate cells (HSCs) is the key event of hepatic fibrosis, and we have previously shown that fibroblast growth factor 7 (FGF7) expression is de novo expressed during HSC-activation while its highly specific receptor FGFR2IIIb is exclusively expressed on hepatocytes in the liver. The aim of this study was characterize the function of FGF7 in chronic liver disease with a focus on non-alcohol…

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B Czech, D Valletta, T Amann, A Bosserhoff, C Hellerbrand (2015) Fibroblast growth factor 7 inhibits hepatic steatosis, inflammation and fibrosis in murine models of on non-alcoholic steatohepatitis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397059

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