CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Hepatic detoxification and anti-oxidative response in liver tissue with cholestasis: analysis of Nrf2 dependent gene expression
DOI 10.1055/s-0034-1397062
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Nachweis in CareLit
Autor:innenA Sahin, R Dayoub, M Thomas, U Zanger, M Melter, TS Weiss
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Cholestasis is a reduction in bile flow induced by a variety of factors resulting in enhanced concentrations of toxic bile acids. It may lead to hepatocellular injury, inflammation, fibrosis, cirrhosis and finally to liver failure. Studies demonstrate that oxidative stress occurs in cholestatic liver tissue and reduction of reactive oxygen species during cholestasis diminish fibrosis. A crucial player in the defense…
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Zitierempfehlung
A Sahin, R Dayoub, M Thomas, U Zanger, M Melter, TS Weiss (2015) Hepatic detoxification and anti-oxidative response in liver tissue with cholestasis: analysis of Nrf2 dependent gene expression. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397062
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