CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Impairment of insulin signaling in hepatocytes by supernatants of insulin-activated macrophages
DOI 10.1055/s-0034-1397066
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Autor:innenRG Camargo, J Henkel, J Manowsky, N Schanze, D Coleman, A Pathe-Neuschäfer-Rube, M Seelaender, GP Püschel
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
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Abstract-Vorschau
Background: Hepatic insulin resistance and hyperinsulinemia are hallmarks in pre-diabetic obese patients. It is generally assumed that hyperinsulinemia is a consequence of the attempt of the body to compensate insulin resistance by enhanced release of insulin from β-cells. Here, evidence is provided that hyperinsulinemia itself might contribute to the development of hepatic insulin resistance by enhancing cytokine p…
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Zitierempfehlung
RG Camargo, J Henkel, J Manowsky, N Schanze, D Coleman, A Pathe-Neuschäfer-Rube, M Seelaender, GP Püschel (2015) Impairment of insulin signaling in hepatocytes by supernatants of insulin-activated macrophages. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397066
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