CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
Increased expression of the Glucose-transporter GLUT1 during hepatic stellate cell activation promotes hepatic fibrosis
DOI 10.1055/s-0034-1397068
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Autor:innenB Czech, D Valletta, A Koch, M Saugspier, A Bosserhoff, C Hellerbrand
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Normal liver reveals only low expression of the facilitative glucose transporter (GLUT) 1. Recently, we have shown that GLUT1 expression is increased in hepatocellular carcinoma (HCC), where GLUT1 acts as a tumor promotor. Hyperglycemia is one of the factors known to induce and promote hepatic fibrogenesis, and the activation of hepatic stellate cells (HSCs) is the key event of hepatic fibrosis. Furthermore, these c…
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Zitierempfehlung
B Czech, D Valletta, A Koch, M Saugspier, A Bosserhoff, C Hellerbrand (2015) Increased expression of the Glucose-transporter GLUT1 during hepatic stellate cell activation promotes hepatic fibrosis. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397068
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