CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
MK2 mediates induction and sensing of Oncostatin M-induced intercellular signalling in the liver but is dispensable for negative feedback regulation via SOCS3
DOI 10.1055/s-0034-1397077
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Autor:innenO Böhmer, C Ehlting, MJ Hahnel, M Thomas, UM Zanger, M Gaestel, WT Knoefel, J Schulte am Esch, D Häussinger, JG Bode
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Oncostatin M (OSM) is expressed in the context of several inflammatory diseases and plays a role in liver regeneration after liver injury. It is mainly secreted by activated T lymphocytes, monocytes and macrophages such as the Kupffer cells of the liver. As a member of the IL-6-type cytokine family it is also involved in the regulation of acute phase protein expression in hepatocytes. Binding of OSM to its cognate r…
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Zitierempfehlung
O Böhmer, C Ehlting, MJ Hahnel, M Thomas, UM Zanger, M Gaestel, WT Knoefel, J Schulte am Esch, D Häussinger, JG Bode (2015) MK2 mediates induction and sensing of Oncostatin M-induced intercellular signalling in the liver but is dispensable for negative feedback regulation via SOCS3. Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397077
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