CareLit · DOI-Nachweis · Zeitschrift für Gastroenterologie
NLRP3 inflammasome expression in cultured hepatocytes is regulated by nuclear factor-κB (NF-κB)
DOI 10.1055/s-0034-1397079
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Nachweis in CareLit
Autor:innenSG Boaru, E Borkham-Kamphorst, E Van de Leur, C Liedtke, R Weiskirchen
ZeitschriftZeitschrift für Gastroenterologie
Ausgabe01/2015
Jahrgang / SeitenNicht angegeben
Kernaussage aus der Literatur
Abstract-Vorschau
Background: The inflammasomes are cytoplasmic multiprotein complexes that are responsible for activation of inflammatory reactions. In principal, there are four individual inflammasome branches (i.e. NLRP1, NLRP3, NLRC4/NALP4, and AIM2) that mediate the cleavage and activation of caspase-1 and IL-1β that in turn leads to a complex network of cellular reactions that at the end initiate local and systemic inflammatory…
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Zitierempfehlung
SG Boaru, E Borkham-Kamphorst, E Van de Leur, C Liedtke, R Weiskirchen (2015) NLRP3 inflammasome expression in cultured hepatocytes is regulated by nuclear factor-κB (NF-κB). Zeitschrift für Gastroenterologie (01). https://doi.org/10.1055/s-0034-1397079
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